Orofacial granulomatosis (OFG) is an uncommon chronic granulomatous condition with a multifactorial etiology and pathogenesis. Genetic, immunologic, allergic, and infectious mechanisms have been implicated. OFG is often used as a descriptor to encompass all entities with orofacial swelling and histologic evidence of noncaseating granulomas.

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Orofacial granulomatosis is also referred to as granulomatous cheilitis, and is characterised clinically by chronic /relapsing swelling of the lips and oral mucosa. Histology of orofacial granulomatosis. In orofacial granulomatosis, sections show oral mucosa with a sparse inflammatory infiltrate and mild oedema (figure 1).

The precise cause of OFG is unknown. Orofacial granulomatosis is a relatively uncommon granulomatous disorder that usually affects young adults and has nearly equal incidence in both sexes. 2 The signs and symptoms include persistent enlargement of soft tissues in and around the mouth and gingiva, oral ulceration, and cobblestoning of the tongue. 2021-04-07 · Orofacial granulomatosis (OFG) is a rare condition characterised by chronic disfiguring oral and facial inflammation which can be very distressing. The incidence, geographical distribution and cause of this disease is not known but is thought to involve an allergic component, the trigger for which is not always clear.

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The precise cause of OFG is unknown. Orofacial granulomatosis is a relatively uncommon granulomatous disorder that usually affects young adults and has nearly equal incidence in both sexes. 2 The signs and symptoms include persistent enlargement of soft tissues in and around the mouth and gingiva, oral ulceration, and cobblestoning of the tongue. 2021-04-07 · Orofacial granulomatosis (OFG) is a rare condition characterised by chronic disfiguring oral and facial inflammation which can be very distressing. The incidence, geographical distribution and cause of this disease is not known but is thought to involve an allergic component, the trigger for which is not always clear. 1.1.1 Orofacial granulomatosis Orofacial granulomatosis (OFG) is a rare granulomatous disease affecting the oral and facial mucosa causing lesions such as lip/facial swelling, angular cheilitis, cobblestone phenomenon, tag formation, mucosal ridges and full thickness gingivitis (1).

Patel P, Brostoff J, Campbell H, et al.

Oro-facial granulomatosis (OFG) is a rare chronic inflammatory disorder presenting characteristically with lip swelling but also affecting gingivae, buccal mucosa, floor of mouth, and a number of other sites in the oral cavity.

Orofacial granulomatosis, describes several conditions in which granulomatous inflammation of soft tissues in the oral and maxillofacial region occur. Such  Abstract.

2016-07-01

in 1985 to describe a rare granulomatous inflammation in the orofacial area in the absence of a systemic condition [1, 2].

Orofacial granulomatosis

OFG is often used as a descriptor to encompass all entities with orofacial swelling and histologic evidence of noncaseating granulomas. Orofacial granulomatosis (OFG) is an uncommon chronic granulomatous condition with a multifactorial etiology and pathogenesis. Genetic, immunologic, allergic, and infectious mechanisms have been implicated. OFG is often used as a descriptor to encompass all entities with orofacial swelling and histologic evidence of noncaseating granulomas. Orofacial granulomatosis (OFG) is an uncommon chronic granulomatous condition with a multifactorial etiology and pathogenesis. Genetic, immunologic, allergic, and infectious mechanisms have been implicated.
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2015 Apr, Vol 4(2): 13-16 13 Case Report Keywords: Diagnosis, Granulomatous conditions, Orofacial granulomatosis, Lip swelling, Multidisciplinary approach DentistrySection Karthikeya Patil, Mahima V Guledgud, Usha Hegde, Ankita Sahni, Bhuvan Nagpal ABSTRACT Orofacial granulomatosis(OFG) is a Orofacial granulomatosis (OFG) is an uncommon chronic inflammatory disorder of the orofacial region. It is characterized by subepithelial noncaseating granulomas and has a spectrum of possible clinical manifestations ranging from subtle oral mucosal swelling to permanent disfiguring fibrous swelling of the lips and face.

1 It has been proposed that OFG with localized granulomatous inflammation of the lips (known as Miescher 2021-04-20 · Orofacial granulomatosis (OFG) is a rare condition characterised by chronic disfiguring oral and facial inflammation which can be very distressing. The incidence, geographical distribution and cause of this disease is not known but is thought to involve an allergic component, the trigger for which is not always clear. Orofacial granulomatosis (OFG) is a rare disease characterized by noncaseating granulomatous inflammation. The most common clinical presentation is persistent swelling of the soft tissues in the oral and maxillofacial regions.
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Orofacial granulomatosis (OFG) is a rare, idiopathic disorder of the orofacial region. It is clinically characterized by persistent and/or recurrent enlargement of the soft tissues of the oral and maxillofacial region, often manifesting as labial enlargement and swelling of intraoral sites such as the gingiva, tongue, and buccal mucosa.

Oro-facial granulomatosis (OFG) is a rare chronic inflammatory disorder presenting characteristically with lip swelling but also affecting gingivae, buccal mucosa, floor of mouth, and a number of other sites in the oral cavity. Orofacial Granulomatosis (OFG) What are the aims of this leaflet?